While tissue engineers have made strides in making complex artificial tissues, such as those of the heart, liver and lungs, creating artificial blood vessels has remained a critical challenge in tissue engineering. The tangled highway of blood vessels that twists and turns inside our bodies performs the crucial task of delivering essential nutrients and disposing hazardous waste to keep our organs working properly. To successfully regenerate organs, tissue engineers will need to make artificial blood vessels as well as organ tissues.
In this video, Ali Khademhosseini, PhD, MASc, a biomedical engineer and the Director of the BWH Biomaterials Innovation Research Center, talks about progress in fabricating blood vessels by using this 3-D bioprinting technique. The first transplantable structures will likely be parts of organs, such as a replacement for heart muscle damaged by myocardial infarction. Dr. Khademhosseini envisions that the same technology will lead to the replacement of bone tissue. He also notes that in the future, 3-D printing technology may be used to develop transplantable tissues customized to each patient’s needs or be used outside the body to develop drugs that are safe and effective.